INNV-32. COMPARING THE MONTREAL COGNITIVE ASSESSMENT (MOCA) FULL AND 5-MINUTE PROTOCOLS IN MILD COGNITIVE IMPAIRMENT SCREENING OF ADULT CNS TUMOR PATIENTS

Abstract BACKGROUND Mild cognitive impairment (MCI) commonly occurs in primary CNS tumor patients (PCTP). Our group and others have reported on the Montreal Cognitive Assessment (MoCA) as an MCI screening tool. Several abbreviated MoCA protocols been developed for telehealth administration other neurological diseases, with varied literature scoring clinical utility. We compared Full 5-minute scores to assess utility neuro-oncology. METHODS 71 PCTP completed (abnormal: < 26/30) assessing: visuospatial/executive functioning, naming, memory, attention, language, abstraction, delayed recall, orientation. were retrospectively recoded Pendlebury protocol 10/12) Correlation was assessed using Pearson’s coefficient. Disagreements between tests examined t-test chi-square test. RESULTS Patients primarily White (83%), college-educated (71%) males (54%) diagnosed glioblastoma (20%), average age of 43 years (range: 19-75), KPS > 80 (57%), prior radiation treatment (78%), imaging surveillance at time testing (79%). mean 25.3 (SD: 4.8) 9.9 2.3), respectively. indicated 32% (n= 23) 27% 19) 5-minute. Where disagreed, detected only by 6 (8%), 2 (3%). Visuospatial/executive (p= 0.025) abstraction (p< 0.001) subdomain scores, unique Full, significantly associated Full; subdomains, patient characteristics, total score not significant. The versions highly correlated (r= 0.90). CONCLUSION High correlation agreement this neuro-oncology population highlight potential Future prospective assessment is warranted describe optimal threshold